Posted 4782 days ago
Pfizer Inc. Is seeking a Principal Scientist for its Kalamazoo, Mich., location. This is a full-time job in pharmaceuticals.
Responsibilities
Pfizer Inc. Is seeking a talented senior scientist to join our efforts in the discovery of novel protein therapeutics for veterinary medicine applications. This job will require an independent thinker with the ability to effectively collaborate with other team members within the department as well colleagues in other technical disciplines. Excellent communication skills are essential. This position will not have any direct reports and will not require significant travel. Scientists with a keen interest in Veterinary Medicine and proven research ability are strongly encouraged to apply.
Specifically, the incumbent will:
1. Serve as Metabolism & Safety representative/subteam leader for multiple concurrent projects
2. Design and manage the conduct of in vitro and in vivo studies in laboratory and veterinary species
3. Ensure that projects receive the correct level of support from all Metabolism and Safety technical disciplines
4. Ensure timely conduct of quantitative bioanalytical assays for large-molecule compounds
5. Prepare reports and present results to scientists and management in group settings
Qualifications
Minimum Qualifications:
• PhD in Biology, Biochemistry, Chemistry, Pharmacology, or related discipline with more than 2 years of ndustry experience (or BS/MS with >10 years of industry experience and more than 2 years experience serving as project team representative/subteam leader for drug discovery/development teams)
• Advanced knowledge of PK, PK/PD, pharmacology, and bioanalytical chemistry, particularly for large molecules (proteins/peptides, oligonucleotides, etc.)
• Comprehensive knowledge of methods for quantitative analysis (LC-MS/MS, immunoassays) and biological sample prep for large molecules (proteins/peptides, oligonucleotides, etc.).
• Working knowledge of principles and concepts in adjacent disciplines for biotherapeutic projects (toxicology, molecular biology, protein/peptide chemistry, drug synthesis/formulation, protein expression/characterization, etc.)
• Demonstrated ability to work collaboratively with colleagues in other disciplines on project teams
• Ability to work under minimum supervision and direction
• Excellent written and oral communication skills
• Fluency with Microsoft Outlook, Word, Excel, PowerPoint
Desired Qualifications
• Experience conducting in vitro and in vivo studies
• Experience with radioisotopes (14C and/or 3H), particularly conducting radioisotope-labeled drug disposition studies
• Familiarity with veterinary species (companion animals and food animals)
• Experience with PK modeling and data acquisition software such as WinNONLIN, WATSON, ANALYST, and others
Marketing Statement
Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. Pfizer discovers, develops, manufactures and delivers quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. The company also partners with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.
Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.